Yes, you can! A variety of political leaders such as candidates for US Senate and local officials from around the world are currently using Donorbox to raise money for their campaigns. You can find out more about political fundraising on Donorbox here.
For US campaigns, there are two features that might be of interest to you:
1. Collect employer and occupation information.
2. Set the max donation amount to comply with campaign laws.
You can also add additional questions to your donation forms if you need to collect more details from your supporters.